Evolutionary BiologybioRxiv
Pathogen to commensal: longitudinal within-host population dynamics, evolution, and adaptation during a chronic >16-year Burkholderia pseudomallei infection
T. Pearson, J. Sahl, C. M. Hepp…·P. Keim
This study tracks the long-term evolution of Burkholderia pseudomallei in a human host over 16 years, showing its transition from a pathogen to a commensal through genetic and phenotypic changes.
DOI 10.1371/journal.ppat.1008298