Author

S. Reiken

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:host-pathogen & immune response· 2 Assay:proteomics· 2 Organism:C. elegans· 1 Research Focus:differential expression· 1 Organism:human· 1 Assay:metabolomics· 1

Frequent Co-Authors

A. R. Marks· 3 shared H. dridi· 2 shared A. Lacampagne· 1 shared A. Robling· 1 shared A. Umanskaya· 1 shared B. A. Hain· 1 shared D. L. Waning· 1 shared F. Forrester· 1 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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3 shared papersCancer Biology

A. R. Marks

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3 papers

Recent·Most cited

Cancer BiologybioRxivPreprintJun 1, 2023

Zoledronic acid improves bone quality and muscle function in a high bone turnover state

T. Trivedi, M. Manaa, S. John…·T. A. Guise

This study shows zoledronic acid improves bone quality and muscle function in a mouse model of metabolic bone disease by reducing TGFβ release from bone.

DOI 10.1101/2023.06.01.543305

mouseexperimental assay

𝕏 PostBluesky

Cell BiologybioRxivDec 5, 2021

Role of oxidation of excitation-contraction coupling machinery in age-dependent loss of muscle function in C. elegans

H. dridi, F. Forrester, A. Umanskaya…·A. R. Marks

This paper shows that oxidative stress causes age-related muscle dysfunction in C. elegans by oxidizing the RyR homolog UNC-68 and reducing its stabilizing subunit FKB-2, leading to calcium leaks and muscle weakness.

DOI 10.7554/elife.75529

C. elegansproteomics

𝕏 PostBluesky

PathologybioRxivPreprintFeb 18, 2021

Alzheimer's-like remodeling of neuronal ryanodine receptor in COVID-19

A. R. Marks, H. Dridi, S. Reiken…·L. Sittenfeld

This paper links SARS-CoV-2 infection to RyR2 channel dysfunction and oxidative stress, showing similar neuropathological pathways as in Alzheimer's Disease.

DOI 10.1101/2021.02.18.431811

humanproteomics

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