Author

A. R. Marks

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Biophysics· 1 Cancer Biology· 1 Cell Biology· 1 Pathology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 4 Research Focus:cell signaling & trafficking· 2 Research Focus:host-pathogen & immune response· 2 Assay:proteomics· 2 Organism:C. elegans· 1 Assay:cryo-EM· 1 Research Focus:differential expression· 1 Organism:human· 1

Frequent Co-Authors

S. Reiken· 3 shared H. dridi· 2 shared A. Lacampagne· 1 shared A. Robling· 1 shared A. Umanskaya· 1 shared B. A. Hain· 1 shared D. L. Waning· 1 shared F. Forrester· 1 shared

Activity by Year

2021-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersCancer Biology

S. Reiken

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Zoledronic acid improves bone quality and muscle function in a high bone turnover state

T. Trivedi, M. Manaa, S. John, S. Reiken, S. Murthy, G. M. Pagnotti, N. S. Dole, Y. She, S. Suresh, B. A. Hain, J. Regan, R. Ofer, L. Wright, A. Robling, X. Cao, , T. A. Guise

This study shows zoledronic acid improves bone quality and muscle function in a mouse model of metabolic bone disease by reducing TGFβ release from bone.

bioRxiv · Jun 1, 2023 · PreprintCancer Biology

Role of oxidation of excitation-contraction coupling machinery in age-dependent loss of muscle function in C. elegans

H. dridi, F. Forrester, A. Umanskaya, W. Xie, S. Reiken, A. Lacampagne, A. R. Marks

This paper shows that oxidative stress causes age-related muscle dysfunction in C. elegans by oxidizing the RyR homolog UNC-68 and reducing its stabilizing subunit FKB-2, leading to calcium leaks and muscle weakness.

bioRxiv · Dec 5, 2021Cell Biology

High resolution structure of the membrane embedded skeletal muscle ryanodine receptor

Z. Melville, K. Kim, O. B. Clarke, A. R. Marks

The paper uses cryoEM to solve high-resolution structures of RyR1 in liposomes, achieving 3.36 and 3.98 Å resolution for closed and open states, respectively.

bioRxiv · Mar 9, 2021Biophysics

Alzheimer's-like remodeling of neuronal ryanodine receptor in COVID-19

A. R. Marks, H. Dridi, S. Reiken, X. Liu, L. Sittenfeld

This paper links SARS-CoV-2 infection to RyR2 channel dysfunction and oxidative stress, showing similar neuropathological pathways as in Alzheimer's Disease.

bioRxiv · Feb 18, 2021 · PreprintPathology