Author

S. Root

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Approach:genetic perturbation / CRISPR· 1 Assay:organoid / primary culture· 1

Frequent Co-Authors

C. J. Lengner· 2 shared F. B. Johnson· 2 shared Q. Chen· 2 shared R. J. Fernandez· 2 shared A. Babu· 1 shared C. T. Berry· 1 shared D. B. Frank· 1 shared D. C. Liberti· 1 shared

Activity by Year

2020-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 40 mutual co-author links

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2 shared papersCell Biology

C. J. Lengner

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Author profile →

2 papers

Recent·Most cited

Patient induced pluripotent stem cell-derived hepatostellate organoids establish a basis for liver pathologies in telomeropathies

Y. Choi, M. S. Kim, J. H. Rhoades, N. M. Johnson, C. T. Berry, S. Root, Q. Chen, Y. Tian, R. J. Fernandez, Z. Cramer, S. Adams-Tzivelekidis, N. Li, F. B. Johnson, C. J. Lengner

The paper uses patient-derived iPS cells to model liver pathologies in telomeropathies and identifies AKT suppression as a potential therapeutic target.

bioRxiv · Nov 19, 2021Cell Biology

GSK3 inhibition rescues growth and telomere dysfunction in dyskeratosis congenita iPSC-derived type II alveolar epithelial cells

R. J. Fernandez, Z. J. G. Gardner, K. J. Slovik, D. C. Liberti, K. N. Estep, W. Yang, Q. Chen, G. T. Santini, J. V. Perez, S. Root, R. Bhatia, J. W. Tobias, A. Babu, M. P. Morley, D. B. Frank, , F. B. Johnson

This study shows that GSK3 inhibition improves growth and telomere function in DC patient-derived AT2 cells by enhancing Wnt signaling.

bioRxiv · Oct 28, 2020Cell Biology