Telomeric DNA breaks in human induced pluripotent stem cells trigger ATR-mediated arrest and telomerase-independent telomere length maintenance
K. N. Estep, J. W. Tobias, R. J. Fernandez…·F. B. Johnson
This study investigates how human iPSCs respond to telomeric DNA breaks, showing ATR-mediated cell cycle arrest and telomerase-independent telomere maintenance via ALT.