Author

S. Hinz

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Bioengineering· 1 Cell Biology· 1 Ecology· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Organism:human· 4 Approach:experimental assay· 3 Assay:proteomics· 3 Research Focus:cell type annotation· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1

Frequent Co-Authors

C. Schafmayer· 2 shared K. Y. Aguilera· 2 shared L. L. Sohn· 2 shared M. A. LaBarge· 2 shared A. Dunkel· 1 shared A. Hendriks· 1 shared A. Mai· 1 shared A. Manousopoulou· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

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2 shared papersCancer Biology

C. Schafmayer

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

ATF6 activation alters colonic lipid metabolism causing tumor-associated microbial adaptation

O. I. Coleman, A. Sorbie, A. Riva, M. von Stern, S. Kuhls, D. Selegato, N. Koehler, J. Wirbel, T. Kacprowski, A. Dunkel, J. K. Pauling, J. Plagge, D. Miedel-Cuadra, S. Wagner, I. Chadly, , D. Haller

This study shows ATF6 activation in colonic epithelial cells alters lipid metabolism, promoting tumor-associated microbial adaptation in mice and human colorectal cancer patients.

bioRxiv · Nov 3, 2023 · PreprintCancer Biology

A new simulation framework to evaluate the suitability of eDNA for marine and aquatic Environmental Impact Assessments

J. Coston-Guarini, S. Hinz, L. Mirimin, J.-M. Guarini

This paper develops a simulation framework to assess eDNA's suitability for detecting environmental impacts in aquatic ecosystems, finding that population dynamics and DNA shedding patterns are critical for detection.

bioRxiv · Dec 15, 2022Ecology

AXL-TBK1 driven nuclear AKT3 promotes metastasis

E. N. Arner, J. M. Westcott, S. Hinz, C. E. Tiron, M. Blo, A. Mai, R. Virtakoivu, N. Z. Phinney, S. Nord, K. Y. Aguilera, A. Rizvi, J. E. Toombs, T. Reese, V. Fey, D. Micklem, , R. A. Brekken

This study identifies AXL-TBK1-driven nuclear AKT3 as a driver of EMT and metastasis, showing that selective AKT3 inhibition reduces tumor progression in breast cancer.

bioRxiv · Jan 17, 2022 · PreprintCancer Biology

Evaluating sources of technical variability in the mechano-node-pore sensing pipeline and their effect on the reproducibility of single-cell mechanical phenotyping

B. Li, K. L. Cotner, N. K. Liu, S. Hinz, M. A. LaBarge, L. L. Sohn

This study evaluates technical variability in a single-cell mechanical phenotyping platform and shows high reproducibility across different labs and users.

bioRxiv · Jun 2, 2021Bioengineering

Deep Proteome Profiling of Human Mammary Epithelia at Lineage and Age Resolution

S. Hinz, A. Manousopoulou, M. Miyano, R. W. Sayaman, K. Y. Aguilera, M. E. Todhunter, J. C. Lopez, L. L. Sohn, L. D. Wang, M. A. LaBarge

The paper profiles the proteome of human mammary epithelia across age and lineage, identifying age-related protein changes and potential therapeutic targets for breast cancer.

bioRxiv · Feb 2, 2021Cell Biology

3D spatially-resolved geometrical and functional models of human liver tissue reveal new aspects of NAFLD progression

F. Segovia-Miranda, H. Morales-Navarrete, M. Kucken, V. Moser, S. Seifert, U. Repnik, F. Rost, A. Hendriks, S. Hinz, C. Rocken, D. Luthjohann, Y. Kalaidzidis, C. Schafmayer, L. Brusch, J. Hampe, M. Zerial

This study creates 3D spatial models of human liver tissue to identify new morphometric parameters and topological defects linked to NAFLD progression.

bioRxiv · Mar 9, 2019Pathology