Single-molecule Mechanical Analysis of Strand Invasion in Human Telomere DNA
T. Chang, X. Long, S. Shastry, J. W. Parks, M. D. Stone
This study uses magnetic tweezers to form telomeric D-loops and shows that displaced DNA folds into G-quadruplexes, providing insight into telomere structure and potential therapeutic targets.
bioRxiv · Jun 22, 2021Biophysics