S. R. Collins

The paper uses CRISPRi screens in human neutrophils to identify genes regulating context-dependent migration and differentiation.

This study predicts microbiota responses to environmental pH and osmolality by analyzing bacterial growth under controlled conditions and identifying predictive genes and pathways.

The paper shows that high and low priority neutrophil attractants elicit distinct signaling dynamics, with high priority signals being sustained and low priority signals being transient.

This study shows neutrophils resolve directional dilemmas by committing to one leading edge late in the decision process, influenced by mechanical stretching and receptor inputs.

This study shows Wnt/PCP signaling promotes breast cancer metastasis by enhancing pro-invasive protrusions in leader cells during collective migration.

This study shows WASP integrates substrate topology and cell polarity to guide neutrophil migration by selectively polymerizing actin at the leading edge.

The paper uses optogenetic tools to show that F-actin and Cdc42 provide distinct negative signals that limit Cdc42 activation during chemotaxis.

This paper improves the iLID optogenetic system by optimizing membrane anchors to enhance local protein recruitment and spatial precision.