BiophysicsbioRxiv
Single-molecule Mechanical Analysis of Strand Invasion in Human Telomere DNA
T. Chang, X. Long, S. Shastry…·M. D. Stone
This study uses magnetic tweezers to form telomeric D-loops and shows that displaced DNA folds into G-quadruplexes, providing insight into telomere structure and potential therapeutic targets.
DOI 10.1021/acs.biochem.1c00448