Author

S. Silver

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Assay:ATAC-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Organism:mouse· 1 Approach:statistical model· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

A. Bric· 1 shared A. Li· 1 shared A. M. Armstrong· 1 shared A. P. Rameshbabu· 1 shared A. Vattay· 1 shared C. D. Adair· 1 shared C. Luu· 1 shared C. Russ· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperCancer Biology

A. Bric

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Targeted genome editing restores auditory function in adult mice with progressive hearing loss caused by a human microRNA mutation

W. Zhu, W. Du, A. P. Rameshbabu, A. M. Armstrong, S. Silver, Y. Kim, W. Wei, Y. Shu, X. Liu, M. A. Lewis, K. P. Steel, Z.-Y. Chen

This study uses genome editing in adult mice with a MIR96 mutation to restore hearing, showing efficacy that improves with earlier intervention.

bioRxiv · Oct 26, 2023 · PreprintBioengineering

In-Depth Characterization and Validation in BRG1-Mutant Lung Cancers Define Novel Catalytic Inhibitors of SWI/SNF Chromatin Remodeling

Z. Jagani, G. Chenail, K. Xiang, G. Bushold, H.-E. C. Bhang, A. Li, G. Elliott, J. Zhu, A. Vattay, T. Gilbert, A. Bric, R. Kikkawa, V. Dubost, R. Terranova, J. Cantwell, , Haas

This study validates novel BRM/BRG1 ATPase inhibitors as chemical probes for SWI/SNF chromatin remodeling and shows their therapeutic potential in BRG1-mut lung cancers.

bioRxiv · Oct 22, 2019 · PreprintCancer Biology