Author

K. Xiang

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3 Cancer Biology· 2

Signature Assays, Organisms & Methods

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Organism:human· 5 Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 3 Assay:proteomics· 2 Approach:statistical model· 2 Assay:ATAC-seq· 1 Assay:bulk RNA-seq· 1 Research Focus:chromatin & epigenetic regulation· 1

Frequent Co-Authors

H. Zhuang· 3 shared T. Li· 3 shared B. Hong· 2 shared H. Fan· 2 shared L. Wang· 2 shared X. Lai· 2 shared Y. Chen· 2 shared Y. Luo· 2 shared

Activity by Year

2019-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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3 shared papersMicrobiology

H. Zhuang

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Chromatin Remodeling in Patient-Derived Colorectal Cancer Models

K. Xiang, E. Wang, G. Rupprecht, J. Mantyh, M. Negrete, G. Sanati, C. Hsu, P. Randon, A. Dohlman, K. Kretzschmar, N. Giroux, S. Ding, L. Wang, J. Prado, Q. Huang, , X. Shen

This study compares chromatin remodeling in colorectal cancer patient-derived models and identifies transcription factors driving differences in growth and drug response.

bioRxiv · Jul 24, 2022Cancer Biology

Inhibition of SAR S-CoV-2 infection and replication by lactoferrin, MUC1 and α-lactalbumin identified in human breastmilk

K. Xiang, X. Lai, Y. Yu, W. Xian, F. Ye, X. Ju, Y. Luo, H. Dong, Y. Zhou, W. Tan, H. Zhuang, T. Li, X. Liu, Q. Ding

This study identifies lactoferrin, MUC1, and α-lactalbumin in human breastmilk as antiviral components that inhibit SARS-CoV-2 infection and replication, including variants.

bioRxiv · Oct 29, 2021 · PreprintMicrobiology

SARS-CoV-2 and Malayan pangolin coronavirus infect human endoderm, ectoderm and induced lung progenitor cells

K. Xiang, B. Hong, X. Lai, Y. Chen, T. Luo, X. An, L. Song, H. Zhuang, H. Fan, T. Li, Y.-G. Tong

This study shows SARS-CoV-2 and GX_P2V can infect human endoderm, ectoderm, and lung progenitor cells derived from hESCs, with some infections blocked by whey protein and Remdesivir.

bioRxiv · Sep 25, 2020 · PreprintMicrobiology

The effect of whey protein on viral infection and replication of SARS-CoV-2 and pangolin coronavirus in vitro

H. Fan, Y. Luo, B. Hong, L. Wang, X. Jin, Y. Chen, Y. Hu, T. Li, H. Zhuang, Y.-H. Zhou, Y.-G. Tong, K. Xiang

This study shows that whey protein from human and other animal milk inhibits SARS-CoV-2 and GX_P2V in vitro by blocking viral attachment, entry, and replication.

bioRxiv · Aug 17, 2020Microbiology

In-Depth Characterization and Validation in BRG1-Mutant Lung Cancers Define Novel Catalytic Inhibitors of SWI/SNF Chromatin Remodeling

Z. Jagani, G. Chenail, K. Xiang, G. Bushold, H.-E. C. Bhang, A. Li, G. Elliott, J. Zhu, A. Vattay, T. Gilbert, A. Bric, R. Kikkawa, V. Dubost, R. Terranova, J. Cantwell, , Haas

This study validates novel BRM/BRG1 ATPase inhibitors as chemical probes for SWI/SNF chromatin remodeling and shows their therapeutic potential in BRG1-mut lung cancers.

bioRxiv · Oct 22, 2019 · PreprintCancer Biology