Increased mitochondrial Ca2+ contributes to health decline with age and Duchene muscular dystrophy in C. elegans.
A. Higashitani, M. Teranishi, Y. Nakagawa, Y. Itoh, S. Sudevan, N. J. Szewczyk, Y. Kubota, T. Abe, T. Kobayashi
This study shows that reducing mitochondrial calcium influx in C. elegans improves age-related and muscular dystrophy muscle decline by mitigating mitochondrial dysfunction.
bioRxiv · Jul 8, 2022Cell Biology