MicrobiologybioRxiv
Principles of dengue virus evolvability derived from genotype-fitness maps in human and mosquito cells
P. T. Dolan, S. Taguwa, M. Aguilar Rangel…·J. Frydman
This study identifies principles of dengue virus evolvability by analyzing genotype-fitness maps in human and mosquito cells, revealing host-specific adaptation mechanisms and genetic load effects.