MicrobiologybioRxiv
Oligomeric state of the ZIKV E protein defines protective immune responses.
S. W. Metz, A. Thomas, A. Brackbill…·A. M. de Silva
This study shows that dimeric Zika E protein antigens induce stronger neutralizing antibodies than monomers, suggesting that mimicking viral quaternary structure improves subunit vaccine efficacy.
DOI 10.1038/s41467-019-12677-6