Cell BiologybioRxiv
The N-terminus of Stag1 is required to repress the 2C program by maintaining rRNA expression and nucleolar integrity
D. Pezic, S. Weeks, W. Varsally…·S. HADJUR
This study identifies the N-terminus of Stag1 as critical for maintaining nucleolar integrity and repressing the 2C program in mESCs by regulating rRNA expression and preventing totipotency.
DOI 10.1016/j.stemcr.2023.09.004