ImmunologybioRxivPreprint
PPa1 insufficiency drives lysosomal storage disease and inflammatory macrophage expansion in the bone marrow.
Magdalena G. Grzemska, Luming Chen, Jamie L. Russell…·Evan Nair‐Gill
DOI 10.64898/2026.03.16.712247
Author
The University of Texas Southwestern Medical Center
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
2 papers
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Magdalena G. Grzemska, Luming Chen, Jamie L. Russell…·Evan Nair‐Gill
Le Xiao, Magdalena G. Grzemska, Xiong Pi…·Evan Nair‐Gill
This paper presents the cryo-EM structure of the Pacs1-Wdr37 complex, revealing its assembly mechanism and stability, and identifies a mutation linked to neurodevelopmental syndrome.