Author

Tüzer Kalkan

Wellcome/MRC Cambridge Stem Cell Institute

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Developmental Biology· 2

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Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cell-cell communication· 1 Approach:statistical model· 1 Research Focus:trajectory inference· 1

Frequent Co-Authors

Austin G SmithiD· 2 shared Carla MulasiD· 2 shared Heather J LeeiD· 1 shared Hendrik G. StunnenbergiD· 1 shared Hendrik MarksiD· 1 shared Isabelle R. E. Nett· 1 shared Jennifer NicholsiD· 1 shared Kathryn Susan LilleyiD· 1 shared

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2017-2017 · peak 2/yr

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10 top collaborators · 45 mutual co-author links

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2 shared papersDevelopmental Biology

Austin G SmithORCID

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2 papers

Recent·Most cited

Developmental BiologyStem Cell ReportsPeer-reviewedJun 29, 2017

Nodal secures pluripotency upon embryonic stem cell progression from the ground state

Carla Mulas, Tüzer Kalkan, Austin G Smith

This study shows that Nodal maintains pluripotency in mouse ES cells as they exit the ground state, enabling competence for germline and somatic lineage specification.

87 citations

mousebulk RNA-seq

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Developmental BiologyDevelopmentPeer-reviewedFeb 7, 2017

Tracking the embryonic stem cell transition from ground state pluripotency

Tüzer Kalkan, Nelly N. Olova, Mila Roode…·Austin G Smith

The paper tracks the transition of mouse embryonic stem cells from ground state pluripotency to a formative phase, showing acute exit from naive status and transcriptome changes similar to early post-implantation epiblast.

289 citationstop 1%

mousebulk RNA-seq

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