T. C. Boothby

This study shows that helical structure in a tardigrade IDP is necessary for desiccation tolerance, but not sufficient on its own.

This study identifies a mechanism by which tardigrade CAHS D proteins form gels to protect cells during desiccation, showing that gelation reduces molecular motion and metabolic activity, with reversible effects.

This study identifies material properties of vitrified systems that correlate with desiccation tolerance in vitro and in organisms, showing that protection depends on distinct properties for different sugars and that organisms combine these properties for survival.

This study shows that natural and engineered desiccation-tolerant mediators can stabilize Human Blood Clotting Factor VIII without cold-chain storage.

This study identifies CAHS D as a tardigrade protein that protects against desiccation through multiple mechanisms involving water coordination and slowed molecular motion.

The paper introduces LITE microscopy, a technique that improves resolution and brightness while reducing photodamage in fluorescence imaging.