Author

T. Dalton

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Organism:mouse· 1 Research Focus:perturbation response prediction· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

A. A. Amparo· 1 shared A. C. Garcia· 1 shared A. J. Aguirre· 1 shared A. Mercante· 1 shared A. R. Decker-Farrell· 1 shared B. Bakir· 1 shared B. Lee· 1 shared B. Metchock· 1 shared

Activity by Year

2018-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperCancer Biology

A. A. Amparo

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Author profile →

2 papers

Recent·Most cited

Tumor-selective effects of active RAS inhibition in pancreatic ductal adenocarcinoma

U. N. Wasko, J. Jiang, A. C. Garcia, Y. Wang, B. Lee, M. Orlen, K. Drizyte-Miller, M. Menard, J. Dilly, S. A. Sastra, C. F. Palermo, T. Dalton, M. C. Hasselluhn, A. R. Decker-Farrell, S. Chang, , R. H Vonderheide

This study evaluates the therapeutic potential of RMC-7977, a broad-spectrum RAS inhibitor, in pancreatic ductal adenocarcinoma models, showing strong anti-tumor effects with minimal impact on normal tissues.

bioRxiv · Dec 3, 2023 · PreprintCancer Biology

Validation of novel Mycobacterium tuberculosis isoniazid resistance mutations not detectable by common molecular tests

J. L. Kandler, A. Mercante, T. Dalton, M. N. Ezewudo, L. Cowan, S. P. Burns, B. Metchock, P. Cegielski, J. E. Posey

The paper identifies novel isoniazid resistance mutations in Mycobacterium tuberculosis using whole genome sequencing and functional validation, showing WGS improves detection of resistance beyond common tests.

bioRxiv · May 15, 2018Microbiology