Author

T. Dieudonne

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:cryo-EM· 1 Research Focus:protein folding & dynamics· 1 Research Focus:protein structure prediction· 1 Assay:structural biology· 1

Frequent Co-Authors

C. Stock· 2 shared G. Lenoir· 2 shared J. A. Lyons· 2 shared P. Nissen· 2 shared C. Jaxel· 1 shared C. Montigny· 1 shared F. Kummerer· 1 shared K. Lindorff-Larsen· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersBiochemistry

C. Stock

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2 papers

Recent·Most cited

BiochemistryNature CommunicationsPeer-reviewedNov 18, 2023

Activation and substrate specificity of the human P4-ATPase ATP8B1

T. Dieudonne, F. Kummerer, M. Juknaviciute Laursen…·P. Nissen

This study presents cryo-EM structures and functional analysis of the human ATP8B1-CDC50A complex, revealing its mechanism of action, substrate specificity, and regulation by phosphoinositides.

DOI 10.1038/s41467-023-42828-9

humancryo-EM

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BiochemistrybioRxivNov 3, 2021

Autoinhibition and regulation by phosphoinositides of ATP8B1, a human lipid flippase associated with intrahepatic cholestatic disorders

T. Dieudonne, S. A. Herrera, M. J. Laursen…·G. Lenoir

This study investigates the autoinhibition and regulation of ATP8B1, a lipid flippase, through functional studies and cryo-EM structure analysis, revealing the role of phosphoinositides and terminal segments in its activity.

DOI 10.7554/elife.75272

humanstructural biology

𝕏 PostBluesky