Author

T. Dunkley

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Biology Disciplines

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Biophysics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1 Assay:protein structure· 1

Frequent Co-Authors

A. Cortes Cabrera· 1 shared A. Topp· 1 shared B. Banfai· 1 shared C. Stucki· 1 shared C.-y. Chen· 1 shared D. Roth· 1 shared E. Melo· 1 shared F. Delobel· 1 shared

Activity by Year

2017-2017 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperBiophysics

A. Cortes Cabrera

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1 paper

Recent·Most cited

HtrA1 activation is driven by an allosteric mechanism of inter-monomer communication

A. Cortes Cabrera, E. Melo, D. Roth, A. Topp, F. Delobel, C. Stucki, C.-y. Chen, P. Jakob, B. Banfai, T. Dunkley, O. Schilling, S. Huber, R. Iacone, P. Petrone

This study elucidates the allosteric mechanism of HtrA1 activation through inter-monomer communication, showing its role in proteolytic activity and disease-related pathologies.

bioRxiv · Jul 14, 2017Biophysics