Author

T. F. Chao

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Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:multiome· 1

Frequent Co-Authors

J. P. Ling· 1 shared L. R. Hayes· 1 shared P. Kalab· 1 shared R. Carmen· 1 shared T. Das· 1 shared V. Trinh· 1 shared X. Zhang· 1 shared

Activity by Year

2023-2023 · peak 1/yr

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7 top collaborators · 21 mutual co-author links

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1 shared paperCell Biology

J. P. Ling

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1 paper

Recent·Most cited

Cell BiologybioRxivAug 1, 2023

Multivalent GU-rich oligonucleotides sequester TDP-43 in the nucleus by inducing high molecular weight RNP complexes

X. Zhang, T. Das, T. F. Chao…·L. R. Hayes

This study shows that multivalent GU-rich oligonucleotides sequester TDP-43 in the nucleus, forming high molecular weight RNPs, but pure GU-repeats impair TDP-43 function.

DOI 10.1016/j.isci.2024.110109

humanmultiome

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