Author

T. Golan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Approach:deep learning· 1 Research Focus:development & morphogenesis· 1

Frequent Co-Authors

A. G. Sowalsky· 1 shared A. Rajan· 1 shared C. A. Iacobuzio-Donahue· 1 shared C. Allen· 1 shared C. Caldas· 1 shared C. H. Dampier· 1 shared C. Stossel· 1 shared D. Kelsen· 1 shared

Activity by Year

2021-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperCancer Biology

A. G. Sowalsky

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3 papers

Recent·Most cited

Prediction of cancer treatment response from histopathology images through imputed transcriptomics

D.-T. Hoang, G. Dinstag, L. C. Hermida, D. S. Ben-Zvi, E. Elis, K. Caley, S.-J. Sammut, S. Sinha, N. Sinha, C. H. Dampier, C. Stossel, T. Patil, A. Rajan, W. Lassoued, J. Strauss, , E. Ruppin

ENLIGHT-DeepPT predicts cancer treatment response from H&E slides by first imputing transcriptomics and then using that data to predict response across multiple therapies and cancer types.

bioRxiv · Jun 7, 2022 · PreprintCancer Biology

Loss of tumor suppressor WWOX accelerates pancreatic cancerdevelopment through promotion of TGFβ/BMP2 signaling

H. Husanie, M. Abu-Remaileh, K. Maroun, L. Abu-Tair, H. Safadi, K. Atlan, T. Golan, R. I. Aqeilan

This study shows that loss of WWOX promotes pancreatic cancer by enhancing TGFβ/BMP2 signaling, leading to increased cancer stemness and macrophage infiltration.

bioRxiv · Mar 10, 2022Cancer Biology

BRCA mutational status shapes the stromal microenvironment of pancreatic cancer linking CLU+ CAF expression with HSF1 signaling

L. Shaashua, M. Pevsner-Fischer, G. Friedman, O. Levi-Galibov, S. Nandakumar, R. Nevo, L. E. Brown, W. Zhang, Y. Stein, H. S. Kim, L. Bojmar, W. R. Jarnagin, N. Lecomte, R. Stok, H. Bishara, , R. Scherz-Shouval

This study shows BRCA mutations in pancreatic cancer alter CAF subtypes, specifically increasing CLU+ CAFs, and links this to HSF1 signaling.

bioRxiv · Aug 18, 2021 · PreprintCancer Biology