Inhibiting the GPI Transamidase Subunit GPAA1 Abolishes CD24 Surface Localization and Enhances Macrophage-Mediated Phagocytosis of Ovarian Cancer Cells
A. K. Mishra, T. Ye, S. Banday, R. P. Thakare, C. C. T.-T. Su, N. N. H. Pham, A. Ali, A. Kulshreshtha, S. R. Chowdhury, T. M. Simone, K. Hu, L. J. Zhu, B. Eisenhaber, S. K. Deibler, K. Simin, , M. R. Green
This study identifies GPAA1 as a regulator of CD24 surface expression and shows that inhibiting GPAA1 enhances macrophage-mediated phagocytosis of ovarian cancer cells.
bioRxiv · Oct 21, 2023 · PreprintCancer Biology