Cell BiologybioRxiv
Suppression of canonical TGF-β signaling enables GATA4 to interact with H3K27me3 demethylase JMJD3 to promote cardiomyogenesis
A. S. Riching, E. Danis, Y. Zhao…·K. Song
The paper identifies how TGF-β signaling inhibition allows GATA4 to interact with JMJD3, promoting cardiomyogenesis by demethylating H3K27me3 at cardiac gene promoters.
DOI 10.1016/j.yjmcc.2020.12.005