T. Noguchi

Transcriptional landscape of the dorsal raphe serotonin neurons rendering stress resiliency

This study identifies gene expression changes in DRN serotonin neurons under antidepressant treatment and depression models, revealing S100a10 as a prodepressive gene and its regulatory pathway.

Contributions of PD1 and PD2 to the difference spectrum in the Soret region in Photosystem II

The paper investigates the contribution of PD1 and PD2 to the difference spectrum in the Soret region of PSII by analyzing mutants and comparing their spectra to wild-type strains.

The Administration Effect of Lactic Acid Bacteria Reducing Environmental Alkyl and Fatty Acid Hydroperoxides on Piglets in the Absence of Antimicrobial Agents and in the Presence of Iron

This study shows that administering LpP1-2 to prepartum sows and piglets improves growth and reduces oxidative stress markers, with benefits persisting into early rearing.

Absorption changes in Photosystem II in the Soret band region upon the formation of the chlorophyll cation radical +

The paper measures absorption changes in Photosystem II's Soret band region caused by the chlorophyll cation radical [PD1PD2]+, showing a 'W-shaped' signal dependent on TyrD and its H-bonding environment.

Comparison of 12 molecular detection assays for SARS-CoV-2

The paper compares 12 SARS-CoV-2 molecular assays using respiratory samples, finding some have 100% specificity and high sensitivity, with recommendations for use with internal controls.

Ameliorative effect of a quinazoline-based bromodomain inhibitor, CN210, on experimentally-induced Crohn's disease-like murine ileitis via inhibition of inflammatory cytokine expression

This study shows that CN210, a quinazoline-based BET inhibitor, reduces inflammation in a murine model of Crohn's disease by inhibiting inflammatory cytokine expression and NF-κB/MAP kinase pathways.

Establishment of an orthodontic retention mouse model and the effect of anti-c-Fms antibody on orthodontic relapse

This study establishes a mouse orthodontic retention model and shows that longer retention and anti-c-Fms antibody reduce orthodontic relapse.