Author

T. Reinheckel

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Research Focus:metabolism & bioenergetics· 1

Frequent Co-Authors

A. Boettcher· 1 shared A. Fearns· 1 shared A. Kostina· 1 shared A. Mallavialle· 1 shared A. Rodgers· 1 shared B. Aylan· 1 shared B. S. Saller· 1 shared C. Agarinis· 1 shared

Activity by Year

2020-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

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Curved chords = mutual co-authorship

1 shared paperImmunology

A. Boettcher

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Cell BiologybioRxivAug 9, 2022

Lysosomal damage drives mitochondrial proteome remodelling and reprograms macrophage immunometabolism

C. Bussi, T. Heunis, E. Pellegrino…·M. G. Gutierrez

This study shows lysosomal damage leads to mitochondrial proteome changes and metabolic reprogramming in macrophages, affecting immune responses to infections.

DOI 10.1038/s41467-022-34632-8

mousebulk RNA-seq

𝕏 PostBluesky

ImmunologybioRxivPreprintFeb 19, 2022

Tyrosine kinase inhibitors trigger lysosomal damage-associated cell lysis to activate the NLRP3 inflammasome

E. Neuwirt, G. Magnani, T. Cikovic…·O. Gross

A small molecule screen identifies tyrosine kinase inhibitors that cause lysosomal damage, leading to cell lysis and NLRP3 inflammasome activation via K+ efflux.

DOI 10.1101/2022.02.19.480941

experimental assayhost-pathogen & immune response

𝕏 PostBluesky

Cancer BiologybioRxivPreprintOct 22, 2020

A 9-kDa matricellular SPARC fragment released by cathepsin D exhibits pro-tumor activity in the triple-negative breast cancer microenvironment

L. B. Alcaraz, A. Mallavialle, T. David…·E. Liaudet-Coopman

The paper identifies a 9-kDa SPARC fragment released by cathepsin D in TNBC that promotes tumor progression by enhancing cell migration and invasion.

DOI 10.1101/2020.10.22.350082

humanproteomics

𝕏 PostBluesky