T. S. Rasmussen

This study develops modified fecal virome transplants (FVT) to reduce donor variability and infection risks in treating C. difficile infections, showing improved efficacy and safety in a mouse model.

The paper investigates how the choice of ultrafilter affects the recovery of bacteriophages from clinical samples, finding that pore size influences recovery strain- and sample-dependently.

Modified fecal virome transplantation improves blood glucose regulation in obese mice without reducing weight gain, while unmodified FVT reduces immune cell proportions in adipose tissue.

This study shows that continuous chemostat cultures reduce eukaryotic viruses in fecal material, suggesting a safer alternative to fecal microbiota transplantation.

This study shows that fecal virome transplantation increases Akkermansia muciniphila abundance in mice and unexpectedly raises fertility rates in co-housed pairs.

This study shows that the CRISPR-Cas system of Eggerthella lenta provides limited phage immunity in vitro and in vivo, allowing coexistence of phage and bacteria in the gut.

This study shows that faecal virome transplantation from lean donors reduces weight gain and improves glucose tolerance in obese mice, suggesting a role for gut viruses in metabolic health.

The paper isolates and characterizes a novel bacterium from an obese mouse's caecum, proposing a new genus and species based on genomic and phenotypic data.

This study shows that differences between mouse vendors have a greater impact on gut bacterial and viral communities than diet.