Author

T. Saio

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Biochemistry· 4

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 4 Research Focus:cell signaling & trafficking· 3 Research Focus:chromatin & epigenetic regulation· 3 Assay:protein structure· 3 Research Focus:protein folding & dynamics· 2 Research Focus:cell type annotation· 1 Organism:human· 1 Assay:protein sequence· 1

Frequent Co-Authors

H. Kumeta· 3 shared M. Matsusaki· 3 shared M. Okumura· 3 shared M. Watabe· 2 shared S. Kanemura· 2 shared C. Hirayama· 1 shared D. Ito· 1 shared E. Mori· 1 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersBiochemistry

H. Kumeta

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Client recognition differences between PDI and ERp46 to guide oxidative folding

T. Saio, K. Ishii, M. Matsusaki, H. Kumeta, S. Kenemura, M. Okumura

The paper compares how PDI and ERp46 recognize client proteins during oxidative folding, showing distinct mechanisms that influence disulfide bond formation and protein quality control.

bioRxiv · Mar 4, 2024 · PreprintBiochemistry

Zinc finger domains bind low-complexity domain polymers

N. Iguchi, N. Isozumi, Y. Hattori, T. Imamura, M. So, H. Nanaura, T. Kiriyama, N. Eura, M. Yamaoka, M. Nakanishi, M. Mori, S. Ohki, H. Kumeta, H. Koga, M. Watabe, , E. Mori

This study shows zinc finger domains bind low-complexity domain polymers in a cross-β-dependent manner, suppressing polymer formation and preferentially recognizing polymeric LC domains.

bioRxiv · Oct 29, 2023 · PreprintBiochemistry

Oxidative phase transition of heat shock factor-1

S. Kawagoe, M. Matsusaki, K. Ishimori, T. Saio

This study shows Hsf1 undergoes oxidative phase transition, forming gel-like droplets that drive cell fate decision via nuclear stress bodies.

bioRxiv · Dec 2, 2021Biochemistry

A unique adhesive motif of protein disulfide isomerase P5 supports its function via dimerization

M. Okumura, S. Kanemura, M. Matsusaki, M. Kinoshita, T. Saio, D. Ito, C. Hirayama, H. Kumeta, M. Watabe, Y. Amagai, Y.-H. Lee, S. Akiyama, K. Inaba

This study identifies a unique adhesive motif in P5 that enables dimerization, which is essential for its structural stability and functional roles in ER quality control.

bioRxiv · Nov 17, 2020Biochemistry