Author

T. Shimi

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 4

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 3 Approach:experimental assay· 3 Assay:imaging· 3 Organism:mouse· 3 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

H. Kimura· 3 shared O. Medalia· 3 shared R. D. Goldman· 3 shared S. A. Adam· 3 shared Y. Kono· 2 shared Y. Zheng· 2 shared A. Kaiho· 1 shared A. Komatsubara· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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3 shared papersCell Biology

H. Kimura

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4 papers

Recent·Most cited

Delayed localization of A-type lamins to the rupture sites in Hutchinson-Gilford progeria syndrome

Y. Kono, C.-G. Pack, T. Ichikawa, A. Komatsubara, S. A. Adam, K. Miyazawa, L. Rolas, S. Nourshargh, O. Medalia, R. D. Goldman, T. Fukuma, H. Kimura, T. Shimi

This study investigates the delayed localization of A-type lamins to nuclear envelope rupture sites in HGPS, identifying farnesylation and proteolytic cleavage as key factors affecting this process.

bioRxiv · Sep 2, 2023Cell Biology

Nucleoplasmic Lamin C Rapidly Accumulates at Sites of Nuclear Envelope Rupture with BAF and cGAS

Y. Kono, S. A. Adam, K. Reddy, Y. Zheng, O. Medalia, R. D. Goldman, H. Kimura, T. Shimi

The paper shows lamin C, BAF, and cGAS accumulate at nuclear envelope rupture sites in mouse cells, with lamin A/C involvement in DNA sensing.

bioRxiv · Jan 5, 2022Cell Biology

RNA polymerase II condensate formation and association with Cajal and histone locus bodies in living human cells

T. Imada, T. Shimi, Y. Saeki, A. Kaiho, H. Kimura

The paper shows that RNA polymerase II condensates form near Cajal and histone locus bodies in human cells, with dynamic interactions during the cell cycle.

bioRxiv · Dec 25, 2020Cell Biology

Computational analysis of lamin isoform interactions with nuclear pore complexes

M. Kittisopikul, T. Shimi, M. Tatli, J. R. Tran, Y. Zheng, O. Medalia, K. Jaqaman, S. A. Adam, R. D. Goldman

The paper analyzes lamin isoform interactions with nuclear pore complexes using microscopy data from mouse fibroblasts, showing their role in maintaining nuclear envelope organization.

bioRxiv · Apr 3, 2020Cell Biology