Differential TM4SF5-mediated SIRT1 modulation and signaling for chronic liver disease
J. Ryu, E. M. Kim, M. Kang, D.-G. Song, E.-A. Shin, J. W. Jung, S.-H. Nam, J. E. Kim, H.-J. Kim, J.-H. Lee, J.-H. Yoon, T. Son, S. Kim, H. Y. Kim, J. W. Lee
This study identifies TM4SF5's role in modulating SIRT1 and STAT3 signaling during NAFL to NASH progression, showing age-dependent effects and potential therapeutic targets.
bioRxiv · Feb 19, 2020 · PreprintCell Biology