Cancer BiologybioRxiv
EZH2/ hSULF1 axis mediates receptor tyrosine kinase signaling to shape cartilage tumor progression
Z.-S. Lin, C.-C. Chung, Y.-C. Liu…·M.-C. Hung
This study identifies the EZH2/SULF1/cMET axis as a driver of chondrosarcoma progression and shows that targeting this pathway can slow tumor growth and improve survival in mouse models.
DOI 10.7554/elife.79432