Author

M.-C. Hung

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3 Biochemistry· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:cancer & tumor microenvironment· 3 Organism:human· 3 Assay:proteomics· 3 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

C.-L. Tsai· 2 shared Y. Chen· 2 shared A. B. Maitra· 1 shared A. Lu· 1 shared B. S. Wong· 1 shared B.-F. Pan· 1 shared B.-Y. Huang· 1 shared C.-C. Chung· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

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2 shared papersCancer Biology

C.-L. Tsai

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

The natural tannins oligomeric proanthocyanidins and punicalagin are potent inhibitors of infection by SARS-CoV-2 in vitro

H.-F. Chen, W.-J. Wang, C.-Y. Chen, W.-C. Chang, P.-R. Hsueh, S.-L. Peng, C.-S. Wu, Y. Chen, H.-Y. Huang, W.-J. Shen, S.-C. Wang, M.-C. Hung

This study identifies OPCs and punicalagin as potent inhibitors of SARS-CoV-2 infection, with punicalagin showing the strongest activity against omicron variants and viral entry.

bioRxiv · Jan 12, 2023Microbiology

Nardilysin-Regulated Scission Mechanism Activates Polo-like Kinase 3 to Suppress the Development of Pancreatic Cancer

J. Fu, J. Li, C.-F. Li, C.-L. Tsai, W. Yin, J. Hou, P. Chen, Y. Cao, Y. Kang, Y. Sun, X. Xia, K. Furukawa, Y. Lu, M. Wu, Q. Huang, , P. Chiao

The paper identifies a post-translational mechanism where Nardilysin cleaves Plk3 to generate an active form that suppresses pancreatic cancer development and metastasis.

bioRxiv · Jul 28, 2022Cancer Biology

EZH2/ hSULF1 axis mediates receptor tyrosine kinase signaling to shape cartilage tumor progression

Z.-S. Lin, C.-C. Chung, Y.-C. Liu, C.-H. Chang, H.-C. Liu, Y.-Y. Liang, T.-L. Huang, T.-M. Chen, C.-H. Lee, C.-H. Tang, Y.-H. Chen, M.-C. Hung

This study identifies the EZH2/SULF1/cMET axis as a driver of chondrosarcoma progression and shows that targeting this pathway can slow tumor growth and improve survival in mouse models.

bioRxiv · Jun 7, 2022Cancer Biology

Post-EMT: Cadherin-11 mediates cancer hijacking fibroblasts

W. Kang, Y. Fan, Y. Du, E. A. Tonkova, Y.-H. Hsu, K. V. Tan, S. Alexander, B. S. Wong, H. Yang, J. Luo, K. Yao, J. Yang, X. Hu, T. Liu, Y. Gan, , Z. Gu

This study identifies cadherin-11 as a mediator of cancer cell hijacking of fibroblasts post-EMT, enhancing invasion and metastasis in solid tumors.

bioRxiv · Aug 27, 2020 · PreprintCancer Biology

Inhibition of Severe Acute Respiratory Syndrome Coronavirus 2 main protease by tafenoquine in vitro

Y. Chen, W.-H. Yang, L.-M. Huang, Y.-C. Wang, C.-S. Yang, Y.-L. Liu, M.-H. Hou, C.-L. Tsai, Y.-Z. Chou, B.-Y. Huang, C.-F. Hung, Y.-L. Hung, J.-S. Chen, Y.-P. Chiang, D.-Y. Cho, , M.-C. Hung

This study identifies tafenoquine as an inhibitor of SARS-CoV-2 main protease, showing it reduces protease activity and inhibits viral infection in vitro.

bioRxiv · Aug 14, 2020 · PreprintBiochemistry