Cell BiologybioRxivPreprint
ACC1-Dependent De Novo Lipogenesis Sustains Hematopoietic Stem Cell Quiescence and Self-Renewal
Morgan Jones, Andrew DeVilbiss, Timothy A Liang…·Qing Li
This study shows that ACC1-dependent de novo fatty acid synthesis is essential for maintaining HSC quiescence and self-renewal, with its loss leading to impaired function and increased fatty acid oxidation.
DOI 10.64898/2026.06.03.729986