Cancer BiologyScientific ReportsPeer-reviewed
Complex genotype-phenotype relationships shape the response to treatment of Down Syndrome Childhood Acute Lymphoblastic Leukaemia
C. Lutz, V. A. Turati, R. Clifford…·T. Enver
This study investigates genotype-phenotype relationships in Down Syndrome ALL, showing that genetic and phenotypic heterogeneity influences treatment response and relapse through clonal competition.
DOI 10.1038/s41598-025-28779-9