Using CombiCells, a platform enabling titration and combinatorial display of cell surface ligands, to study T cell antigen sensitivity by TCRs, CARs, and BiTEs
A. Patel, V. Andre, S. Bustamante Eguiguren, M. I. Barton, J. Burton, E. M. Denham, J. Pettmann, A. M. Morch, M. Kutuzov, J. A. Siller-Farfan, M. L. Dustin, P. A. van der Merwe, O. Dushek
The paper uses CombiCells to compare T cell antigen sensitivity mediated by TCRs, CARs, and BiTEs and assess the impact of co-stimulation and co-inhibition receptors.
bioRxiv · Jun 15, 2023 · PreprintImmunology