Author

V. H. Bustos

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Biology Disciplines

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Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

A. Bispo· 1 shared A. Jedlicki· 1 shared A. Lam· 1 shared A. Sinha· 1 shared E. Chang· 1 shared E. Mui· 1 shared H. Rosenthal· 1 shared M. Flajolet· 1 shared

Activity by Year

2023-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperPharmacology & Toxicology

A. Bispo

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1 paper

Recent·Most cited

Pharmacology & ToxicologybioRxivApr 28, 2023

Rational development of a small-molecule activator of CK1γ2 that decreases C99 and beta-amyloid levels

V. H. Bustos, Y. K. Sunkari, A. Sinha…·S. Sinha

This study identifies CK1γ2 as a therapeutic target for Alzheimer's disease by showing its activation reduces C99 and beta-amyloid levels through increased PS1-Ser367 phosphorylation.

DOI 10.1021/acschembio.3c00425

humanproteomics

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