Author

V. Hejret

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Pathology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:cell-cell communication· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Assay:proteomics· 2 Approach:biophysical modeling· 1

Frequent Co-Authors

B. Tichy· 2 shared A. P. Gerber· 1 shared A. R. Perestrelo· 1 shared A. Tiefenbacher· 1 shared B. Neudert· 1 shared C. Binder· 1 shared C. d. J. Cardona· 1 shared C. Sternberg· 1 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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2 shared papersCancer Biology

B. Tichy

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Cell-autonomous GP130 activation suppresses prostate cancer development via STAT3/ARF/p53-driven senescence and confers an immune-active tumor microenvironment

C. Sternberg, T. Limberger, M. Raigel, K. Trachtova, M. Schlederer, D. Lindner, P. Kodajova, J. Yang, R. Ziegler, H. A. Neubauer, S. Dey, T. Redmer, S. Stoiber, V. Hejret, B. Tichy, , L. Kenner

This study shows that activating GP130 in prostate epithelial cells suppresses tumor growth through senescence and immune activation, suggesting a new therapeutic approach.

bioRxiv · Feb 11, 2024 · PreprintCancer Biology

Mimicking tumor cell heterogeneity of colorectal cancer in a patient-derived organoid-fibroblast model

V. S. Atanasova, C. d. J. Cardona, V. Hejret, A. Tiefenbacher, L. Tran, C. Binder, T. Mair, J. Kabiljo, J. Clement, K. Woeran, B. Neudert, M. Hengstschlaeger, M. Mitterhauser, L. Muellauer, B. Tichy, , G. Egger

This paper develops a colorectal cancer organoid model incorporating patient-derived fibroblasts, showing enhanced cellular heterogeneity and morphology compared to mono-cultures.

bioRxiv · Mar 7, 2022Cancer Biology

The mechanical regulation of RNA binding protein hnRNPC in the failing heart

F. Martino, N. M. Varadarajan, A. R. Perestrelo, V. Hejret, H. Durikova, V. Horvath, F. Cavalieri, F. Caruso, W. S. Albihlal, A. P. Gerber, M. A. O'Connell, S. Vanacova, S. Pagliari, G. Forte

The paper shows that hnRNPC upregulation and relocation to the Z-disk in failing hearts affects mRNA alternative splicing and mechanotransduction.

bioRxiv · Aug 27, 2021Pathology