Metabolic Reprogramming Driven by Ant2 -Targeting Augments T-Cell Function and Anti-Tumor Immunity
O. Yosef, L. Cohen-Daniel, O. Shamriz, Z. Bar-On, A. Saragovi, I. Abramovich, B. Agranovich, V. Lutz, J. Tam, A. Permyakova, E. Gottlieb, M. Huber, M. Berger
This study shows that Ant2 deficiency enhances T-cell function and anti-tumor immunity by altering mitochondrial metabolism and metabolic reprogramming.
bioRxiv · Apr 21, 2024 · PreprintImmunology