Author

D. Soll

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Evolutionary Biology· 2 Immunology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Research Focus:drug response / drug discovery· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Assay:proteomics· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

C. E. Zielinski· 2 shared H. S. Kwok· 2 shared S. V. Melnikov· 2 shared A. van den Elzen· 1 shared A. Welle· 1 shared B. Michalke· 1 shared C. C. Thoreen· 1 shared C.-F. Chu· 1 shared

Activity by Year

2018-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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2 shared papersImmunology

C. E. Zielinski

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Sodium chloride in the tumor microenvironment enhances T-cell metabolic fitness and cytotoxicity

D. Soll, M. Arunkumar, M. Alissa-Alkhalaf, S. Sun, T. Nguyen, C.-F. Chu, V. Lutz, S. Schauble, I. Garcia-Ribelles, M. Mueller, B. Michalke, G. Panagiotou, P. Schatzlmaier, H. Stockinger, W. Schamel, , C. E. Zielinski

This study shows sodium chloride enhances CD8+ T-cell metabolic fitness and cytotoxicity, improving tumor cell killing in vitro and in vivo.

bioRxiv · Sep 14, 2023Immunology

Exploiting evolutionary trade-offs to combat antibiotic resistance

S. V. Melnikov, D. L. Stevens, X. Fu, H. S. Kwok, J.-T. Zhang, Y. Shen, J. Sabina, K. Lee, H. Lee, D. Soll

The paper demonstrates that antibiotic-resistant cells can be inhibited by exploiting fitness trade-offs using norvaline to target genetic mutations in leucyl-tRNA synthetase in tavaborole-resistant E. coli.

bioRxiv · Jan 20, 2020 · PreprintEvolutionary Biology

Archaeal ribosomal proteins possess nuclear localization signal-type motifs: implications for the origin of the cell nucleus

S. V. Melnikov, H. S. Kwok, K. Manakongtreecheep, A. van den Elzen, C. C. Thoreen, D. Soll

The paper identifies NLS-type motifs in archaeal ribosomal proteins, showing they can functionally substitute eukaryotic NLSs and suggesting NLSs predate the nucleus.

bioRxiv · Jun 14, 2019Evolutionary Biology

Sodium chloride is an ionic checkpoint for human Th2 cell responses and shapes the atopic skin microenvironment

J. Matthias, J. Maul, R. Noster, H. Meinl, Y.-Y. Chao, H. Gerstenberg, F. Jeschke, G. Gilles, A. Welle, J. Walter, K. Nordstroem, K. Eberhardt, D. Renisch, S. Donakonda, P. Knolle, , C. E. Zielinski

This study shows sodium chloride promotes Th2 cell responses and shapes the atopic skin microenvironment, suggesting it as a therapeutic target for Th2-mediated diseases.

bioRxiv · Aug 13, 2018Immunology