Author

V. Pascal

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Cancer Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:human· 3 Research Focus:cell type annotation· 2 Organism:mouse· 2 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:metabolism & bioenergetics· 1 Assay:metabolomics· 1

Frequent Co-Authors

C. Sirac· 2 shared M. Cogne· 2 shared M. V. Ayala· 2 shared S. Bender· 2 shared A. Bonaud· 1 shared A. Jaccard· 1 shared A. Repetto· 1 shared A. Saintamand· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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2 shared papersImmunology

C. Sirac

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

NNV024, a novel humanized anti-CD37 antibody with enhanced ADCC and prolonged plasma half-life in human FcRn transgenic mice for treatment of NHL

R. Generaloc, E. Fiorito, S. Foss, V. Pascal, H. Heyerdahl, A. Repetto, J. T. Andersen, G. Tjonnfjord, S. S. Skanland, J. Dahle

This paper develops NNV024, a humanized anti-CD37 antibody with enhanced ADCC and prolonged plasma half-life, showing improved efficacy against NHL and CLL cells compared to existing therapies.

bioRxiv · Jul 12, 2023 · PreprintCancer Biology

New models to study plasma cells in mouse based on the restriction of IgJ expression to antibody secreting cells.

M. V. Ayala, A. Bonaud, S. Bender, J.-M. Lambert, F. Lechouane, C. Carrion, M. Cogne, V. Pascal, C. Sirac

The paper introduces two new mouse models, IgJGFP and IgJCreERT2, for studying plasma cells by leveraging IgJ expression as a marker for antibody-secreting cells.

bioRxiv · Aug 13, 2020 · PreprintImmunology

Full-length immunoglobulin high-throughput sequencing reveals specific novel mutational patterns in POEMS syndrome

S. Bender, V. Javaugue, A. Saintamand, M. V. Ayala, M. Alizadeh, M. Filloux, V. Pascal, N. Gachard, D. Lavergne, F. Auroy, M. Cogne, F. Bridoux, C. Sirac, A. Jaccard

This study uses high-throughput Ig repertoire sequencing to identify specific mutational patterns in POEMS syndrome, aiding in diagnosis and detection of low-abundance plasma cell clones.

bioRxiv · Oct 31, 2019Immunology

A metabolic pathway for bile acid dehydroxylation by the gut microbiome

M. Funabashi, T. Grove, V. Pascal, Y. Varma, M. McFadden, L. Brown, C. Guo, M. H. Medema, S. Almo, M. A. Fischbach

This paper completes the metabolic pathway for bile acid dehydroxylation by the gut microbiome and demonstrates its heterologous expression in a non-producing commensal.

bioRxiv · Sep 5, 2019Microbiology