V. Raghuram

Average Nucleotide Identity based Staphylococcus aureus strain grouping allows identification of strain-specific genes in the pangenome

This study uses ANI to group S. aureus strains and identifies strain-specific genes in the pangenome by analyzing gene distribution patterns.

A community-curated, global atlas of Bacillus cereus sensu lato genomes for epidemiological surveillance

The paper develops BTyperDB, a global atlas of Bacillus cereus sensu lato genomes, to improve pathogen surveillance and identify emerging lineages.

Experimentally Evolved Staphylococcus aureus Survives in the Presence of Pseudomonas aeruginosa by Acquiring Mutations in the Amino Acid Transporter, GltT

This study identifies mutations in the amino acid transporter GltT that enable Staphylococcus aureus to survive in the presence of Pseudomonas aeruginosa through altered glutamate metabolism.

Efficacy of a Pseudomonas aeruginosa Serogroup O9 Vaccine

This study develops a vaccine against Pseudomonas aeruginosa serogroup O9 using an attenuated Salmonella strain expressing the O9 LPS, showing it induces protective immunity in mice.

Comparison of genomic diversity between single and pooled Staphylococcus aureus colonies isolated from human colonisation cultures.

This study compares genetic diversity metrics between single-colony and pooled sequencing of Staphylococcus aureus from human colonisation cultures, finding that pool-seq can accurately detect multi-ST populations and clinically relevant genes.

Overproduction of the AlgT sigma factor is lethal to mucoid Pseudomonas aeruginosa

This study shows that overproduction of AlgT sigma factor is lethal in mucoid Pseudomonas aeruginosa and identifies mutations in mucP as suppressors that stabilize MucA22 to reduce toxicity.

Non-canonical cell death by reassortant reovirus

This paper investigates how a reassortant reovirus induces non-conventional caspase-dependent cell death in TNBC cells and links this to host genetic factors.

Genotypic and phenotypic diversity of Staphylococcus aureus from cystic fibrosis lung infections and their interactions with Pseudomonas aeruginosa

This study analyzes the genotypic and phenotypic diversity of Staphylococcus aureus from cystic fibrosis lung infections and their interactions with Pseudomonas aeruginosa, finding that isolates retain virulence factors and exhibit varied survival responses to P. aeruginosa.

Analysis of Vibrio cholerae genomes using a novel bioinformatic tool identifies new, active Type VI Secretion System gene clusters

The paper develops a bioinformatic tool to identify new T6SS gene clusters in V. cholerae and demonstrates the function of a newly discovered effector protein.