Author

D. Gerlach

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Microbiology· 3 Cancer Biology· 2

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 4 Organism:human· 4 Research Focus:cancer & tumor microenvironment· 2 Research Focus:drug response / drug discovery· 2 Research Focus:host-pathogen & immune response· 2 Research Focus:perturbation response prediction· 2 Assay:proteomics· 2 Research Focus:cell type annotation· 1

Frequent Co-Authors

A. Peschel· 2 shared K. Kostyrko· 2 shared M. H. Hofmann· 2 shared A. A. Machado· 1 shared A. Bitzer· 1 shared A. Frank· 1 shared A. Hendriks· 1 shared A. Jeschko· 1 shared

Activity by Year

2020-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersMicrobiology

A. Peschel

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Systematic classification of phage receptor-binding proteins predicts surface glycopolymer structure in Staphylococcus pathogens

J. Krusche, C. Beck, E. Lehmann, D. Gerlach, C. Wolz, A. Peschel

The paper develops a computational pipeline to classify phage receptor-binding proteins and predicts surface glycopolymer structure in Staphylococcus pathogens.

bioRxiv · Mar 4, 2024 · PreprintMicrobiology

Nasal commensals reduce Staphylococcus aureus proliferation by restricting siderophore availability

Y. Zhao, A. Bitzer, J. J. Power, D. Belikova, B. Torres-Salazar, L. A. Adolf, D. Gerlach, B. Krismer, S. Heilbronner

The paper shows nasal commensals reduce S. aureus growth by consuming its siderophores, revealing inter-species competition and potential for probiotic strategies.

bioRxiv · Feb 20, 2024 · PreprintMicrobiology

SOS1 inhibition enhances the efficacy of and delays resistance to G12C inhibitors in lung adenocarcinoma

B. R. Daley, N. E. Sealover, E. Sheffels, J. M. Hughes, D. Gerlach, M. H. Hofmann, K. Kostyrko, B. Mair, A. Linke, Z. Beckley, A. Frank, C. L. Dalgard, R. L. Kortum

This study shows that SOS1 inhibition with BI-3406 enhances G12C inhibitor efficacy and delays resistance in lung adenocarcinoma by targeting resistance mechanisms and drug-tolerant persister cells.

bioRxiv · Dec 7, 2023 · PreprintCancer Biology

Combined KRASG12C and SOS1 inhibition enhances and extends the anti-tumor response in KRASG12C-driven cancers by addressing intrinsic and acquired resistance

V. Thatikonda, H. Lu, S. Jurado, K. Kostyrko, C. A. Bristow, K. Bosch, N. Feng, S. Gao, D. Gerlach, M. Gerlach, S. Lieb, A. Jeschko, A. A. Machado, E. D. Marszalek, M. Mahendra, , M. H. Hofmann

This study shows that combining KRASG12C and SOS1 inhibitors improves anti-tumor response and delays resistance in KRASG12C-driven cancers.

bioRxiv · Jan 23, 2023Cancer Biology

The impact of Staphylococcus aureus cell wall glycosylation on langerin recognition and Langerhans cell activation

A. Hendriks, R. van Dalen, S. Ali, D. Gerlach, G. A. van der Marel, F. F. Fuchsberger, P. Aerts, C. J. C. de Haas, A. Peschel, C. Rademacher, J. van Strijp, J. D. Codee, N. M. van Sorge

This study investigates how different glycosylation patterns on Staphylococcus aureus cell walls affect langerin recognition and Langerhans cell activation, finding that β-GlcNAc is sufficient for langerin binding regardless of its position on WTA.

bioRxiv · Nov 6, 2020Microbiology