PhysiologybioRxivPreprint
TRiPPing the sensors: The osmosensing pathway of Polycystin 2
Karla M. Márquez‐Nogueras, Ryne M. Knutila, V. Vuchkosvka, Ivana Y. Kuo
This study identifies osmolarity as a physiological activator of ER-localized PC2 and shows that MAP4-dependent microtubule stabilization is required for PC2's role in osmosensing and urine concentration.
3 citations