Cell BiologyArteriosclerosis Thrombosis and Vascular BiologyPeer-reviewed
IL-1β inhibition partially negates the beneficial effects of diet-induced lipid lowering
Santosh Karnewar, Vaishnavi Karnewar, Rebecca A. Deaton…·Gary K. Owens
This study shows that inhibiting IL-1β in mice reduces the beneficial effects of diet-induced lipid lowering on atherosclerosis, increasing plaque burden and decreasing plaque stability.