Cell BiologybioRxivPreprint
Activation of GPR116/ADGRF5 by its tethered agonist requires key amino acids in extracellular loop 2 of the transmembrane domain
J. P. Bridges, C. Safina, B. Picard…·M.-G. Ludwig
This study identifies key amino acids in extracellular loops 2/3 and transmembrane7 of GPR116 that are critical for tethered agonist-mediated activation.
DOI 10.1101/2021.04.01.438115