Alphavirus infection triggers selective cytoplasmic translocation of nuclear RBPs with moonlighting antiviral roles
W. Kamel, V. Ruscica, A. Embarc-Buh, Z. R. de Laurent, M. Garcia-Moreno, Y. Demyanenko, M. Madhusudhan, L. Iselin, A. Järvelin, M. Hannan, E. Kitano, S. Moore, A. Merits, I. Davis, S. Mohammed, A. Castello
This study identifies nuclear RNA-binding proteins that are translocated to the cytoplasm during alphavirus infection and exhibit antiviral activity.
bioRxiv · Oct 6, 2021Microbiology