Cancer BiologybioRxiv
Subclonal evolution and expansion of THY1-positive cells is associated with recurrence in glioblastoma
W. N. Al-Holou, H. Wang, V. Ravikumar…·A. Rehemtulla
This paper identifies THY1-positive, mesenchymal/stem-like cells as drivers of glioblastoma recurrence and shows that targeting TGFβ signaling can restore sensitivity to therapy.
DOI 10.1016/j.neo.2022.100872