Author

A. Rehemtulla

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Cell Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Research Focus:cancer & tumor microenvironment· 2 Assay:proteomics· 2 Assay:spatial transcriptomics· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Approach:deep learning· 1

Frequent Co-Authors

A. Pal· 2 shared A. de Carvalho· 1 shared A. Rao· 1 shared A. V. Mathew· 1 shared C. A. Lyssiotis· 1 shared C. Liu· 1 shared C. Speers· 1 shared C. Stansbury· 1 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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2 shared papersCancer Biology

A. Pal

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

A molecularly engineered lectin destroys EGFR and inhibits the growth of non-small cell lung cancer

S. M. Chan, Z. Raglow, A. Pal, S. D. Gitlin, M. Legendre, D. Thomas, R. K. Mehta, M. Tan, M. K. Nyati, A. Rehemtulla, D. Markovitz

This paper demonstrates that the engineered lectin H84T binds to and inhibits NSCLC cell growth by lysosomal degradation of EGFR, independent of EGFR mutation status.

bioRxiv · Mar 18, 2024 · PreprintCancer Biology

A lipid-associated macrophage lineage rewires the spatial landscape of adipose tissue in early obesity

C. Stansbury, G. A. Dotson, H. Pugh, A. Rehemtulla, I. Rajapakse, L. A. Muir

This paper identifies a novel lipid-associated macrophage (LAM) phenotype in early obesity that contributes to crown-like structure formation through specific ligand-receptor interactions.

bioRxiv · Feb 26, 2022Cell Biology

Subclonal evolution and expansion of THY1-positive cells is associated with recurrence in glioblastoma

W. N. Al-Holou, H. Wang, V. Ravikumar, M. Oneka, R. Verhaak, H. Kim, D. Pratt, S. Camelo-Piragua, C. Speers, D. Wahl, S. Shankar, T. Hollon, O. Sagher, J. Heth, K. Muraszko, , A. Rehemtulla

This paper identifies THY1-positive, mesenchymal/stem-like cells as drivers of glioblastoma recurrence and shows that targeting TGFβ signaling can restore sensitivity to therapy.

bioRxiv · Sep 10, 2021Cancer Biology

Mitochondrial Complex II In Intestinal Epithelial Cells Regulates T-cell Mediated Immunopathology

H. Fujiwara, A. V. Mathew, I. Kovalneko, A. Pal, H.-J. Lee, D. Peltier, S. Kim, C. Liu, K. Oravecz-Wilson, L. Li, Y. Sun, J. Byun, T. Saunders, A. Rehemtulla, C. A. Lyssiotis, , P. Reddy

This study identifies mitochondrial complex II disruption in intestinal epithelial cells as a key driver of T-cell mediated intestinal immunopathology across multiple disease models.

bioRxiv · Mar 12, 2020Immunology