Author

W. Roque

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 3

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 3 Organism:human· 3 Assay:bulk RNA-seq· 2 Approach:experimental assay· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:gene regulatory network inference· 1 Assay:metabolomics· 1

Frequent Co-Authors

D. Sales· 2 shared F. Romero· 2 shared I. O. Rosas· 2 shared K. Cuevas-Mora· 2 shared A. J. Halayko· 1 shared A. Wheelock· 1 shared C. J. Britto· 1 shared C.-x. Li· 1 shared

Activity by Year

2020-2020 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersCell Biology

D. Sales

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Decreased miR-24-3p potentiates DNA damage responses and increases susceptibility to COPD

J. Nouws, F. Wan, E. Finnemore, W. Roque, S. Kim, I. Bazan, C.-x. Li, M. Skold, X. Yan, V. Neumeister, C. J. Britto, R. Bindra, A. Wheelock, J. Gomez-Villalobos, N. Kaminski, , M. Sauler

The paper identifies miR-24-3p as a regulator of DNA damage responses and COPD susceptibility, showing its suppression in COPD and its role in modulating apoptosis and DNA repair.

bioRxiv · May 22, 2020 · PreprintCell Biology

Transcriptomics, metabolomics and lipidomics of chronically injured alveolar epithelial cells reveals similar features of IPF lung epithelium

W. Roque, K. Cuevas-Mora, D. Sales, W. V. Li, I. O. Rosas, F. Romero

This study uses an in vitro model of chronic alveolar epithelial injury to reveal transcriptomic, metabolomic, and lipidomic features similar to those in IPF lung epithelium.

bioRxiv · May 8, 2020 · PreprintCell Biology

Impaired HSF1 transactivation drives proteostasis collapse and senescent phenotype of IPF lung fibroblast.

K. Cuevas-Mora, W. Roque, D. Sales, J. D. Ritzenthaler, E. Torres-Gonzales, A. J. Halayko, I. O. Rosas, J. Roman, F. Romero

This study shows that impaired HSF1 transactivation leads to proteostasis collapse and senescent phenotype in IPF lung fibroblasts, suggesting HSF1 activation could treat lung fibrosis.

bioRxiv · Apr 10, 2020 · PreprintCell Biology